This text compiled by leading expert in the field, offers the readers a fundamental understanding about how these cells can contribute to a lot of intriguing and obscure aspects of cancer pathogenesis (i.e., cancer cell dormancy, ...
Book Title: Advances in Cancer Stem Cell Biology
Author:Roberto Scatena,Alvaro Mordente,Bruno Giardina
Published on 2011-10-06 by Springer Science & Business Media
ISBN: 9781461408093 / 1461408091
Total Page: 343
Book Category:Medical
Book is About: Carcinoma Cancer
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In recent years, cancer stem cells have been recognized as important component in carcinogenesis and they seem to form the basis of many (if not all) tumor types. Cancer stem cells or |cancer cell like stem cells| have been isolated from various cancers of different origin (blood, breast, brain, skin, head and neck, thyroid, cervix, lung, retina, colon, pancreas and so on). Cancer stem cells - rare cells with indefinite proliferative potential that drive the formation and growth of tumours- seem to show intriguing relationships with physiological stem cells. Specifically, these cancer cells show significant similarities in the mechanisms that regulate self-renewal of normal stem cells. Moreover, tumour cells might directly arise from normal stem cells. Further, the cellular biology of cancer stem cells show a lot of similarities with normal stem cells.
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