The aim of this study was to evaluate the histologic characteristics incorporating the defined invasion types and distinguish the features that can reflect prognosis. We reviewed all slices of 132 patients with lung squamous carcinoma.
Book Title: Invasion Types Are Associated With Poor Prognosis in Lung Squamous Carcinoma Patients
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Published on 2015 by
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Book is About: Carcinoma
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Abstract : Abstract: Although the prognostic significance of the histologic patterns in lung adenocarcinoma is being identified, no significant prognostic indicators in lung squamous carcinoma are accepted as a standard universally. The aim of this study was to evaluate the histologic characteristics incorporating the defined invasion types and distinguish the features that can reflect prognosis. We reviewed all slices of 132 patients with lung squamous carcinoma. The cases were classified according to the World Health Organization (WHO) classification and were evaluated for tumor budding, single cell invasion, large cell invasion, cytologic atypia degree, mitotic count, number of buds, tumor nest size, fibrosis, and necrosis. In univariate analysis, overall survival was associated significantly with age ( P = 0.023), lymph nodes metastasis ( P
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