Perforin better highlighted the intraepithelial spread of SC than EMA. Ber‐EP4 was strongly expressed in six of nine SC, but was consistently negative in sebaceomas.
Book Title: Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas
Author:
Published on 2016 by
ISBN: /
Total Page:
Book Category:
Book is About: Carcinoma
Download Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas eBook
Abstract: Purpose: Eyelid sebaceous carcinoma (SC) remains a common diagnostic pitfall for both the clinician and histopathologist. The aim of this study was to describe perforin as a new marker in the immunohistochemistry panel for SC. Methods: A total of 29 cases were retrieved from the Pathology archives, including 11 sebaceous neoplasms (nine SC; two sebaceomas), 10 squamous cell carcinomas (SCC) and eight basal cell carcinomas (BCC). These were stained using the monoclonal antibody for perforin, epithelial membrane antigen (EMA), Ber‐EP4 and adipophilin (ADP). Sensitivity and specificity of perforin as an immunohistologic marker for sebaceous tumours were compared to EMA, ADP and Ber‐EP4. Results: Perforin stained strongly 9/11 (81%) of the sebaceous neoplasms (SN), 7/9 SC and 2/2 of sebaceomas (2/2), similar to ADP. Epithelial membrane antigen (EMA) stained 8/9 SC and was negative (1/2) or only very weakly expressed (1/2) in sebaceomas. The specificity of perforin in identifying SN versus SCC and BCC was 100% (95% CI 69–100), while EMA specificity in identifying SN varied according the comparison group (SCC: 50%, 95% CI 18–81, 100% (95% CI 63–100). Perforin better highlighted the intraepithelial spread of SC than EMA. Ber‐EP4 was strongly expressed in six of nine SC, but was consistently negative in sebaceomas. Conclusions: The expression pattern of perforin in sebaceous neoplasms enables us to recommend the use of perforin as a new immunohistochemical marker for sebaceous neoplasms.
Our website offers free Carcinoma Ebooks to download. Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas is the one of great book to have from us, a free ebooks portal, the best free ebooks download library. You can find and download free ebooks in categories. No registration is required to download free e-books. We have huge collection of Carcinoma and ebooks. Each downloadable ebook has a short review with a description. You can find over thousand of ebooks that are free to download. Get ton of books with us, the open directory for free ebooks and download links, the best place to read ebooks and search free download ebooks.Carcinoma ebooks free
download Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas ebook as PDF, EPUB, MOBI, AZW and AZW3, FB2, DJVU, LIT, RFT, IBA, LRS, LRF, and LRX.
download ebooks
There are so many ebooks about Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas that are available to have. Thinking of having Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas ebook? You are in the right place. Get the ebook Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas by: .
Book Details:
- Book was ranked at 31 by Google Books for Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas
- Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas published by since 2016 with ISBNs. The book ISBN 13 Code is and ISBN 10 Code is
- Reading Mode in Text Status is false and Reading Mode in Image Status is false
- The book has " Pages" is Printed at BOOK under Category
- Rated by Raters and have average rate at ""
- eBook written in en
- Book Preview Address: http://books.google.com/books?id=98vrvQEACAAJ&dq=Carcinoma&hl=&cd=230&source=gbs_api
Book Preview
The Button is not working? Try The Alternative links for "Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas by: ":
- Server 2: SECURE LINK